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When added to standard bronchodilator therapies in the two six-month studies, a clear trend for the reduction of exacerbations was observed with roflumilast, over and above what was achieved with these therapies alone.
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* Bosentan because liver problems may occur; the effectiveness of both medicines may be decreased
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"We hope it is a rare event, and we must monitor closely what happens next," he told BBC News. Purchase generic Premarin in Hollywood Flomax Medicine
Roflumilast is a new PDE4 inhibitor being developed specifically to target the chronic inflammation which is COPD-related.